Opportunity Information: Apply for HRSA 21 036
The Sickle Cell Disease Newborn Screening Follow-up Program (HRSA 21-036) is a discretionary federal funding opportunity run by the U.S. Department of Health and Human Services through the Health Resources and Services Administration (HRSA). It is offered as a cooperative agreement, which typically means funded recipients are expected to work closely with HRSA in implementing the program rather than operating with complete independence. The overall aim is to strengthen what happens after a newborn screening result suggests a baby may have sickle cell disease, so that families do not get lost between screening, confirmatory diagnosis, and ongoing care.
At its core, the program focuses on improving access to timely, high-quality sickle cell disease care starting at the earliest possible point: the newborn screening notification. Funding is intended to support active outreach to families from the moment a screen indicates possible SCD, continuing through confirmatory testing, entry into appropriate treatment, and long-term follow-up. This includes helping families navigate next steps, reducing delays in diagnosis, and supporting continuity of care so that children with SCD are connected to the right services early, when prevention measures and routine care can have the greatest impact.
A major component of the opportunity is education and information-sharing. Recipients are expected to provide education to both families and healthcare providers, helping parents and caregivers understand the condition, immediate priorities after diagnosis, and how to access specialized care. On the provider side, the program supports better awareness of evidence-based practices and the importance of rapid follow-up after a positive newborn screen. In addition to direct education, the program emphasizes disseminating practical resources that families and clinicians can use, which can include guidance materials, referral tools, and information about local and regional SCD support services.
The notice also highlights coordination and collaboration as essential. Awardees are expected to work in partnership with state newborn screening programs, since those programs are the gateway for identifying infants who need follow-up. The goal is to strengthen the handoff from screening programs to clinical care systems and community supports, improving how information flows and ensuring that follow-up is consistent and reliable. This collaboration is meant to help close gaps that can occur when screening identifies risk but families face barriers such as limited specialist availability, transportation issues, insurance challenges, or lack of familiarity with SCD care pathways.
Another central expectation is linking individuals and families to broader community resources and care coordination. The program is designed to connect families not only to clinical services but also to supportive services in the communities where they live, to the fullest extent possible. That includes helping families access evidence-based sickle cell care, connect with comprehensive SCD programs when available, and coordinate among primary care, hematology specialists, hospitals, and community-based supports. The intent is to create a more connected support system around the child and family, rather than leaving them to navigate complex systems alone.
From a funding perspective, the opportunity listed an award ceiling of $184,000 per award and anticipated making about 20 awards. The opportunity was created on February 22, 2021, with an original application closing date of April 29, 2021. The CFDA number associated with this funding is 93.110. Eligibility is listed broadly as "Others," with additional details referenced in the full eligibility section of the notice, indicating that applicants needed to consult the announcement for the specific types of organizations allowed to apply.
Overall, this grant opportunity is about making newborn screening results meaningful in practice by ensuring that a positive screen for sickle cell disease triggers fast, organized follow-up that leads to diagnosis, education, treatment initiation, and long-term connection to coordinated, evidence-based care and community supports. The program is structured to reduce delays, improve navigation for families, strengthen provider and family knowledge, and build partnerships between screening systems, healthcare systems, and community resources so that children identified through newborn screening can get the right care as early and as consistently as possible.Apply for HRSA 21 036
- The Department of Health and Human Services, Health Resources and Services Administration in the health sector is offering a public funding opportunity titled "Sickle Cell Disease Newborn Screening Follow-up Program" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.110.
- This funding opportunity was created on Feb 22, 2021.
- Applicants must submit their applications by Apr 29, 2021. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $184,000.00 in funding.
- The number of recipients for this funding is limited to 20 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Frequently Asked Questions (FAQs)
What is the Sickle Cell Disease Newborn Screening Follow-up Program (HRSA 21-036)?
The Sickle Cell Disease Newborn Screening Follow-up Program (HRSA 21-036) is a discretionary federal funding opportunity from the U.S. Department of Health and Human Services (HHS), administered through the Health Resources and Services Administration (HRSA). Its purpose is to strengthen what happens after a newborn screening result suggests a baby may have sickle cell disease (SCD), so families move quickly from screening to confirmatory diagnosis and into appropriate, ongoing care.
What is the main goal of this program?
The main goal is to improve access to timely, high-quality SCD care starting as early as possible, beginning at the point when the newborn screening program notifies a family that the screen indicates possible SCD. The program is designed to reduce delays, prevent families from getting lost in the handoff between systems, and support continuity of care over time.
What stage of care does the program focus on?
The program focuses on the follow-up period after a newborn screening result indicates possible sickle cell disease. This includes outreach to families, confirmatory testing, entry into treatment, and long-term follow-up to help ensure children are connected to the right services early and consistently.
What kinds of activities are intended to be supported with the funding?
Funding is intended to support active outreach and follow-up beginning immediately after a positive newborn screen for possible SCD. Supported activities include helping families navigate next steps, reducing delays in confirmatory diagnosis, supporting entry into appropriate treatment, and maintaining long-term follow-up so care remains connected and coordinated.
Does the program require direct outreach to families?
Yes. A core expectation described in the opportunity is active outreach to families from the moment a screen indicates possible SCD, continuing through confirmatory testing, entry into treatment, and ongoing follow-up.
What does "confirmatory testing" mean in the context of this program?
Within the context of the opportunity, confirmatory testing refers to the steps that occur after a newborn screening result suggests possible SCD, with the goal of confirming the diagnosis and ensuring the child enters appropriate care without unnecessary delays.
How does the program address delays between screening and care?
The program is aimed at reducing delays by creating a fast, organized follow-up process after a positive newborn screen. This includes outreach, navigation support for families, strengthening the handoff from screening programs to care systems, and promoting continuity of care so children reach diagnosis and treatment as soon as possible.
What is meant by "long-term follow-up" in this opportunity?
Long-term follow-up, as described, involves ongoing efforts to keep children with SCD connected to appropriate treatment and coordinated services over time, rather than ending support after confirmatory testing or initial entry into care.
What role does education play in this program?
Education and information-sharing are major components. Recipients are expected to provide education to families and healthcare providers to improve understanding of sickle cell disease, immediate priorities after diagnosis, and how to access specialized care. The opportunity also emphasizes sharing practical resources that families and clinicians can use.
Who should receive education under this program?
The opportunity specifically highlights two groups: (1) families (parents and caregivers) and (2) healthcare providers. Family education focuses on understanding the condition and navigating care; provider education focuses on evidence-based practices and the importance of rapid follow-up after a positive newborn screen.
What types of resources are expected to be shared or disseminated?
The opportunity emphasizes disseminating practical resources such as guidance materials, referral tools, and information about local and regional SCD support services, alongside broader education efforts for families and clinicians.
Is collaboration with state newborn screening programs required or encouraged?
Collaboration is described as essential. Awardees are expected to work in partnership with state newborn screening programs, since those programs serve as the gateway for identifying infants who need follow-up.
Why is coordination with newborn screening programs considered important?
The goal is to strengthen the handoff from screening programs to clinical care systems and community supports, improve how information flows, and ensure follow-up is consistent and reliable. This is intended to close gaps that can occur after a baby is identified as at risk but families face barriers.
What kinds of barriers is the program designed to help address?
The notice points to gaps that can occur when families face barriers such as limited specialist availability, transportation issues, insurance challenges, or lack of familiarity with SCD care pathways. The program aims to strengthen coordination and navigation to reduce these barriers to timely follow-up and care.
Does the program include care coordination beyond clinical services?
Yes. The opportunity emphasizes linking individuals and families to broader community resources and supportive services in addition to clinical care, to the fullest extent possible. The intent is to help families connect to both healthcare and community-based supports.
What kinds of care connections are awardees expected to support?
Awardees are expected to help connect families with evidence-based sickle cell care, comprehensive SCD programs when available, and coordinated services across primary care, hematology specialists, hospitals, and community-based supports.
How is this funding opportunity structured: grant or cooperative agreement?
This opportunity is offered as a cooperative agreement. As described in the notice summary, this typically means funded recipients are expected to work closely with HRSA in implementing the program rather than operating with complete independence.
Which federal agency runs this opportunity?
The opportunity is run by the U.S. Department of Health and Human Services (HHS) through the Health Resources and Services Administration (HRSA).
What is the CFDA number for this program?
The CFDA number associated with this funding opportunity is 93.110.
How much funding is available per award?
The listed award ceiling is $184,000 per award.
How many awards were anticipated?
The opportunity anticipated making about 20 awards.
When was the opportunity created and when did applications close?
The opportunity was created on February 22, 2021, and the original application closing date was April 29, 2021.
Who was eligible to apply?
Eligibility is listed broadly as "Others," with additional details referenced in the full eligibility section of the notice. Applicants were expected to consult the announcement for the specific types of organizations allowed to apply.
What outcomes is this program trying to achieve for families and children?
Based on the description provided, the program aims to ensure that a positive newborn screen triggers fast, organized follow-up leading to confirmatory diagnosis, education, treatment initiation, and long-term connection to coordinated, evidence-based care and community supports. The overall intent is to improve continuity, reduce delays, and make newborn screening results meaningful in real-world practice.
Browse more opportunities from the same category: Health
Next opportunity: Youth Journalism Development Program
Previous opportunity: U.S. Embassy Dakar Public Affairs Section Request for Statements of Interest
Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for HRSA 21 036
Applicants also applied for:
Applicants who have applied for this opportunity (HRSA 21 036) also looked into and applied for these:
| Funding Opportunity |
|---|
| Sickle Cell Disease Treatment Demonstration Program Apply for HRSA 21 032 Funding Number: HRSA 21 032 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Improving HIV/TB Policy Implementation in the KwaZulu Natal (KZN) Province in South Africa under the President's Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH21 2133 Funding Number: CDC RFA GH21 2133 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| Strengthening Public Health Responses and Accelerating HIV/AIDS Program for the Sustainable Provision of Comprehensive HIV/AIDS Services in Oromia Regional State of the Federal Democratic Republic of Ethiopia under PEPFAR Apply for CDC RFA GH21 2109 Funding Number: CDC RFA GH21 2109 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| ACL National Chronic Disease Self-Management Education Resource Center Apply for HHS 2021 ACL AOA CSSG 0020 Funding Number: HHS 2021 ACL AOA CSSG 0020 Agency: Department of Health and Human Services, Administration for Community Living Category: Health Funding Amount: $2,000,000 |
| NIDCR Award for Sustaining Outstanding Achievement in Research (SOAR) (R35 Clinical Trial Not Allowed) Apply for RFA DE 22 001 Funding Number: RFA DE 22 001 Agency: Department of Health and Human Services, National Institutes of Health Category: Health Funding Amount: $650,000 |
| NIH Faculty Institutional Recruitment for Sustainable Transformation (FIRST) Program: FIRST Coordination and Evaluation Center (U24 Clinical Trial Not Allowed) Apply for RFA RM 21 019 Funding Number: RFA RM 21 019 Agency: Department of Health and Human Services, National Institutes of Health Category: Health Funding Amount: $840,000 |
| Childhood Lead Poisoning Prevention and Surveillance of Blood Lead Levels in Children Apply for CDC RFA EH21 2102 Funding Number: CDC RFA EH21 2102 Agency: Department of Health and Human Services, Centers for Disease Control - NCEH Category: Health Funding Amount: $850,000 |
| Capacity Building for Sustainable HIV Services Apply for HRSA 21 064 Funding Number: HRSA 21 064 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Collecting Violent Death Information Using the National Violent Death Reporting System (NVDRS) Apply for CDC RFA CE21 2105 Funding Number: CDC RFA CE21 2105 Agency: Department of Health and Human Services, Centers for Disease Control - NCIPC Category: Health Funding Amount: $942,085 |
| Medication Assisted Treatment - Prescription Drug and Opioid Addiction Apply for TI 21 006 Funding Number: TI 21 006 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $1,000,000 |
| Health Information Systems Strengthening for Improved Public Health Care and Program Management in Haiti under the President's Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH21 2113 Funding Number: CDC RFA GH21 2113 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| Strategic Prevention Framework for Prescription Drugs Apply for SP 21 001 Funding Number: SP 21 001 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $384,000 |
| Development of a COVID-19 Monitoring System for U.S. Correctional and Detention Facilities Apply for CDC RFA PS21 2107 Funding Number: CDC RFA PS21 2107 Agency: Department of Health and Human Services, Centers for Disease Control - NCHHSTP Category: Health Funding Amount: Case Dependent |
| Community Action for HIV Control Activity Apply for 72012121RFA00001 Funding Number: 72012121RFA00001 Agency: Agency for International Development, Ukraine USAID-Kiev Category: Health Funding Amount: $19,500,000 |
| Strengthening HIV/AIDS-related Strategic Information, Laboratory Support, and Technical Assistance Services in Angola under the President's Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH21 2148 Funding Number: CDC RFA GH21 2148 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| ACL National Falls Prevention Resource Center Apply for HHS 2021 ACL AOA FPSG 0019 Funding Number: HHS 2021 ACL AOA FPSG 0019 Agency: Department of Health and Human Services, Administration for Community Living Category: Health Funding Amount: $1,000,000 |
| Behavioral Health Workforce Development Technical Assistance and Evaluation (BHWD TAE) Program Apply for HRSA 21 086 Funding Number: HRSA 21 086 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Preventing Violence Affecting Young Lives (PREVAYL) Apply for CDC RFA CE21 2104 Funding Number: CDC RFA CE21 2104 Agency: Department of Health and Human Services, Centers for Disease Control - NCIPC Category: Health Funding Amount: $250,000 |
| State Newborn Screening Interoperability Implementation Program Apply for HRSA 21 085 Funding Number: HRSA 21 085 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Long-term Follow-up for Severe Combined Immunodeficiency and Other Newborn Screening Conditions Apply for HRSA 21 079 Funding Number: HRSA 21 079 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: $500,000 |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Inside Our Applicants Portal
Access Applicants Portal
- Grants Repository - Access current and historic funding opportunities with ease. Thousands of funding opportunities are published every week. We can help you sort through the database and find the eligible ones to apply for.
- Applicant Video Guides - The grant application process can be challenging to follow. We can help you with intuitive video guides to speed up the process and eliminate errors in submissions.
- Grant Proposal Wizard - We have developed a network of private funding organizations and investors across the United States. We can reach out and submit your proposal to these contacts to maximize your chances of getting the funding you need.
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Learn More
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "HRSA 21 036", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.