Opportunity Information: Apply for RFA AG 26 002
The funding opportunity titled "Single Source: National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD) (U24 Clinical Trial Not Allowed)" is a discretionary National Institutes of Health (NIH) grant announcement from the National Institute on Aging (NIA). It is issued as a cooperative agreement, meaning the awardee is expected to carry out the work with substantial NIH program involvement rather than operating entirely independently. The activity is categorized under health research and support, and it falls under CFDA 93.866. The announcement makes clear that this is a single-source, non-competitive action: NIA intends to make one award and has identified Indiana University Indianapolis as the planned recipient to operate and maintain the National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD). Because it is explicitly non-competitive and single-source, the practical effect is that the opportunity is not designed for open competition in the way most NIH funding announcements are.
The purpose of the award is to support NCRAD, which is described as a national centralized repository serving Alzheimer's disease and related dementias (AD/ADRD). While the summary text in the notice is brief, the title and mechanism strongly indicate that the work centers on repository operations and infrastructure that enable AD/ADRD research across studies. In practice, centralized repositories like NCRAD typically manage standardized processes for receiving, processing, storing, tracking, and distributing research biospecimens and associated data or metadata, and they often provide quality control, chain-of-custody documentation, and harmonized procedures across multiple contributing projects. The "U24" mechanism is commonly used for resource-related and cooperative infrastructure projects, which aligns with the idea of NCRAD as a shared national research resource rather than a single hypothesis-driven research project. The label "Clinical Trial Not Allowed" means the award cannot be used to conduct a clinical trial as defined by NIH policy, reinforcing that the primary work is expected to be repository and research-enabling functions rather than interventional human subjects research.
The opportunity number is RFA-AG-26-002, and the original closing date listed is 2025-10-17. The award ceiling is $9,230,000, indicating the maximum amount anticipated under this announcement. The notice lists the eligible applicant category as public and state-controlled institutions of higher education, but it simultaneously states the agency's intent to issue the award to Indiana University Indianapolis as a single-source cooperative agreement. It also specifies that non-U.S. entities (foreign organizations) are not eligible to apply, and non-U.S. components of U.S. organizations are not eligible to apply, though foreign components as defined in the NIH Grants Policy Statement are allowed. In NIH terms, that generally means a U.S. awardee may include certain foreign collaborations or performance sites if they meet NIH policy requirements, but the primary applicant organization must be U.S.-based and eligible.
Overall, this announcement is best understood as a formal notice that NIA plans to continue or initiate support for NCRAD through a single cooperative agreement award, with a substantial budget cap and a focus on sustaining a centralized national resource for AD/ADRD research. The structure and wording signal continuity of a key research infrastructure function, with eligibility language included for compliance and transparency even though the award is intended to be made without competition.Apply for RFA AG 26 002
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Single Source: National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD) (U24 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866.
- This funding opportunity was created on 2025-06-26.
- Applicants must submit their applications by 2025-10-17. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $9,230,000.00 in funding.
- Eligible applicants include: Public and State controlled institutions of higher education.
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